Hello, I wanted to weigh in with my Ocotype dx score of 22, and get a second opinion.
I am 50 years old, and had mastectomy of left breast two weeks ago showing a 1.2 cm tumor, invasive carcinoma with ductal and
lobular features, no lymphatic or vascular invasion, all margins clear, ER & PR positive, HER2 negative, showing a low
proliferative index, stage 1, grade 2. Only one node removed, the sentinel node, and no cancer cells found. Surgeon and
pathology from Dana Farber Cancer Institute.
Below is more data from my path report:
e-cadherin positive
ERA 99%
PRA 60%
HER2 negative (1 )
Ki67 5%
I was on Premarin since 1993 and stopped July 2 with my biopsy results.
I have a strong history of sensitivity to meds so chemo really scares me. I have a heart arrhythmia that can not be treated
because the meds made my blood pressure drop dangerously, so I am fiercely protective of my heart, and I know breast cancer
chemo can be hard on the heart.
My onco doc says my 22 score is Oncotype midrange is a gray area and doesn't really have a recommendation for me, saying I
have a 14% chance of distant recurrance in 10 years after taking 7 years of hormonal treatment (which I will do), and that
chemo could possibly give me another 2 to 4 percent, which may be as low as 1% and as high (but unlikely) as 6%.I have a
second opinion scheduled for Monday.
This is a difficult decision and wondered if you had any input they might share with me? Also, do you agree with the survival
rate?
Thank you.
Thank you.