Home   Recent Questions   Ask Oncologist    Health Forums   Testimonials   FAQs

This question was answered on Wed 28, Jul 2010 08:07pm by Dr Dennis S, MD

High IGM, RBC, Hemoglobin, Hematocrit and low WBC

Asked by miya (Female; 38; extreme fatigue, bone pain in leg, ribs, back shoulder blade and joints, weight loss, poor appetite, hair loss, weakness, mental confusion, impaired memory, seizure history, impaired immune response, Mono at 15 and relapsing/chronic EBV ) on Tue 27, Jul 2010 04:19pm
Priced at $29.00

A recent blood test showed high protein levels (8.4), so my doctor ordered a PE and IFE, CBC among other tests to follow-up. The results of those tests showed: WBC: 3.6 (low), RBC: 5.54 (high), Hemoglobin: 17.1 (high), Hematocrit: 49.9 (high), and IGM 242 (high) with 'Kappa and lambda typing appearing increased.' The PE scan is pending. Sed rate is 1. Can you help me to interpret these findings? Prior to this, I had an appointment with The Cleveland Clinic in Ohio set for August 12 with their rheumatology/immunology dept. and am wondering also if I am heading to the right department as I continue with the testing/diagnostic. Thank you.

Actions: | Forward |



Security code
Enter the text as shown above

E-Mail me when someone replies to this post
Answer by Dr Dennis S, MD  on Wed 28, Jul 2010 08:07pm:

Hi Miya. Do you also have the differential count of your cbc? Your white blood cell count is lower than normal, which could mean that there is an ongoing infection. An empiric antibiotic therapy can be instituted after appropriate cultures are done. Other causes of decrease in white blood cell count include intake of certain drugs like penicillins and steroids. Autoimmune disorders and hematologic disorders are also causes. Aside from consulting a rheumatologist, you may also want to consult a hematologist and/or an infectious disease specialist for further evaluation. Regards.

If you find the site useful, please consider making a donation.  Click the button to donate.   

Please rate my answer (select the stars, no need to log in.)  

Follow up:

Clarification by miya on Thu 29, Jul 2010 06:42pm:
Yes, it appears to be a CBC w/differential.  Would you like some of those numbers? I am taking no other drugs
(incidentally, am allergic to penicillins).   Doctor said he wanted to do the PE/IFE to identify the reason
for the elevated protein and check for indication of Multiple Myeloma.  The results state there was no M-spike
observed. However, Immunoglobulin M came back high, as I said.  Immunofixation result showed an apparent
Polyclonal Gammopathy; IGM - Kappa lambda typing appear increased. No fever or unusual symptoms since last
batch of tests run a couple of months ago, however, the blood counts have changed from the normal results from
a couple months ago.  I am experiencing pain and feeling of fullness that has been waking me up at night since
this batch of tests done last week. Perhaps spleen?  He also ordered an MRI for an apparent complex partial
seizure he believes I had in his office (thought it was blood sugar, but came back normal when he tested it
there) which I haven't had performed as of yet. -- Hepatitis B/C antigens, Thyroid Peroxidase,
Thyroglobulin antibodies, Lyme, and ANA all came back negative.  Rheumatoid factor, C-reactive tests done
prior to this (recently) were negative.  Complete metabolic panel, T-Cell activation, CD-8 subsets, T + B
Lymphocyte diff., Helper T- Lymph CD-4 and Kappa Lambda free light chains were also tested.  Any further
insights with this information?  I assume they cross-evaluate their findings with other specialists outside
the rheumatology dept., but will request a hematologist and/or infectious disease specialist, if I find that
they do not.  Thank you.
Clarification by miya on Thu 29, Jul 2010 06:47pm:
Sorry, I didn't specify where the pain was:  just below my left ribs, left/mid side of abdomen, hence
'spleen'.  Thanks.

This question is open for comments.  Please share your opinion.




Security code
Enter the text as shown above

E-Mail me when someone replies to this post
Other cancer questions you might be interested in.
  1. Cancer? fever and a pain on the left side of my body near my ovaries and a pain near my liver  (Answered) - Viewed 7163 times   Back in august I had an MRI, because of severe headaches, nausea, loss of feeling in myy right hand, and fainting( dizzines too)...
  2. sclc metastasized to lymph nodes and bones-stage IV  (Answered) - Viewed 1626 times   Which counts in your CBC blood work tell if the chemo is working? Her hemoglobin has been 9.8 9.2 8.1 8.2after a transfusion it ...
  3. Cancer uteri after successful radiotherapy of cervical cancer  (Answered) - Viewed 2079 times   Woman, 65 yo, with hystory of myoma uteri, diabetes and hypertension has been diagnosed with cervical cancer stage IIb-III(verif...
  4. Multinodal cabcer uteri - effective treatment of lymphostasis/edema  (Answered) - Viewed 2227 times   Woman, 65 yo, with history of myoma uteri, diabetes and hypertension has been diagnosed with cervical cancer stage IIb-III(verif...
  5. hemoglobin D disease  (Answered) - Viewed 2113 times   i am a pediatric oncologist in iraq, i have a case of hemoglobin D diseas, i just want to know any thing about this disease. th...
  6. Differential WBC counts..does it mean anything?  (Answered) - Viewed 3126 times   I Had a routine blood test done during physical exam in 2008 and there was a difference observed in WBC differential counts. (Lo...
  7. female, 48, chronic cough, servere anemia  (Answered) - Viewed 1674 times   hello there, i have a question regarding my mum. she is 48, on no medications, never had any health problems in her life. for...
  8. Melanoma metastasis  (Answered) - Viewed 1222 times   Dear doctor, My father (age 58, non-smoker, previous health condition excellent) was diagnosed with metastatic malignant mela...
  9. Soft-tissue tumor in foot  (Answered) - Viewed 2037 times   I have a soft tissue tumor in my left foot, between the first and second metatarsal. It is inside of my foot, just deep to the ...
  10. lymphoma  (Answered) - Viewed 1330 times   Bone marrow biopsy shows: (...a white count of 7.2 hemoglobin 12.2 MCV 86 platelet count 185 and approximate differential of 50...

What users are searching right now on Ask an oncologist now:
kappa protein in the blood     whatisagolfballsizebellythatshows     whatdoctorshouldiseeforalivercyst     soft20tissue20sarcoma     iliac lymph node     impressionair20trapping20in20lung     hpvandanalcancer492120Enter20your20comments20here20starting     subcutaneous20tumor     mesenteric252Blymph252Bnode     nodular20density     erprnegativeher2neupositiv     anal lump     no monoclonal proein     momoclonal IgMLamda     TUMOR     Stage1brenalcellcarcinoma     papseam plan     kidney stones     have20breast20cancer20thats20spread20are20the20itchy20lumps20on20back20of20head20connected     Are plyps dangerous     loss20of20sense20of20smelltaste     list     zometaandmultiplemylenoma     too20many20blood20cells20in20headbrain20symptoms     lowconcentrationmonoclonaligGKAPPA     al252520amyloidosis     pancratic20syst     nonhodgkins     fcnafullform     stage20420lung20cancer20avastin20treatment     IS     pancoast20tumour     what20is20periceliac     fcnafullform     what disease is caused by kappa protein in blood     SIGNS OF LYMPHOMA     Swollen20occipital20lymph20nodes     Result20chosen20nickname2022Tedsgedycig223b20registered2028registering20only20mode20is20ON293b     highwbcandlymphocytes     bronchial252520cancer     varicocele     what20is20wrong20if20your20stomach20hurts20whwen20you20eat     prostatecancerShouldIgothroughany     evolutiveaspectsofnonmetastatucbreastcancerafterinitialtreatments     faint20ill20defined20band20of20IgM20lambda20in20serum     breast20cancergrade203chemo20or20not     free lambda light chain     rectal cancer     kappa20level20344     how20large20is20a203mm20cyst     measuring up to 10 mm in short axisdiameter which isliklyno further reactive adenopathy     low igg     pain on swallowing     hyperthyroidandleftneckmass     jawline     IGGKappaMonoclonalProteinPresentandPossibleMSpikeintheGammaRegionM4445iggkappamonoclonalprotein     platelet20morph     IgG gamma monoclonal protein     Hyaluronic20acid     blockage     Kappalambdalowratio     monoclonal20protein20with20kappa20light20chain     left20eye20swallen20and20side20of20face20swallen     stomach20cancer     thoracic     Tamoxifen     lung cancer untreated     can breast radiation raise cea score     What could be causing a palpable lump in the upper right of my back     LUMPLumpinthebackofn     do you have to smoke to get lung cancer     bronchial cancer     lymphomapeasizedrubberytohardnoduleabovejawlin     igglambdamonoclonalband     multiplemylema     enlargedperipancreaticlymphnodes     sore20lymph20nodes     KidneyCancer     lumpinthighmucsle     small cluster microcalcifications     hard20lump20mons20pubis     teitz Syndtome     endoxan side effect     POUCHOFDOUGLAS     hpvandanalcancer4921 Enter your comments here resynchronization     normal20IgG20with20monoclonal20peak     mold ball in lung     hpvandanalcancer4921 Enter your comments here resynchronization     2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2B2BResult2Bchosen2Bnickname2B22Orillahiele223b2Blogged2Bin3b2Bno2Bpost2Bsending2Bforms2Bare2Bfound3b     tracemonoclonalprotein     how big are hemoroids     chronicinfectionofthroat     low proliferation rate     TRIPLE NEGATIVE INA SENTENCE     suv     bronchialcancer     multiple myeloma igg kappa     oral     pelvic20exenteration     IgG lamba protein in urine     

©2011 - Ask an oncologist now  |  All Rights Reserved
The site is not a replacement for professional medical opinion, examination, diagnosis or treatment. Always seek the advice of your medical doctor or other qualified health professional before starting any new treatment or making any changes to existing treatment. Do not delay seeking or disregard medical advice based on information written by any author on this site. No health questions and information on askanoncologistnow is regulated or evaluated by the Food and Drug Administration and therefore the information should not be used to diagnose, treat, cure or prevent any disease without the supervision of a medical doctor. Posts made to these forums express the views and opinions of the author, and not the administrators, moderators, or editorial staff and hence askanoncologistnow and its principals will accept no liabilities or responsibilities for the statements made.

Home | Terms & Conditions | Contact Us | Frequently Asked Questions | Disclaimer | Privacy Policy | Advertise with us