Home   Recent Questions   Testimonials   FAQs


This question was answered on Wed 28, Jul 2010 08:07pm by Dr Dennis S, MD

High IGM, RBC, Hemoglobin, Hematocrit and low WBC


    
Asked by miya (Female; 38; extreme fatigue, bone pain in leg, ribs, back shoulder blade and joints, weight loss, poor appetite, hair loss, weakness, mental confusion, impaired memory, seizure history, impaired immune response, Mono at 15 and relapsing/chronic EBV ) on Tue 27, Jul 2010 04:19pm
Priced at $29.00

A recent blood test showed high protein levels (8.4), so my doctor ordered a PE and IFE, CBC among other tests to follow-up. The results of those tests showed: WBC: 3.6 (low), RBC: 5.54 (high), Hemoglobin: 17.1 (high), Hematocrit: 49.9 (high), and IGM 242 (high) with 'Kappa and lambda typing appearing increased.' The PE scan is pending. Sed rate is 1. Can you help me to interpret these findings? Prior to this, I had an appointment with The Cleveland Clinic in Ohio set for August 12 with their rheumatology/immunology dept. and am wondering also if I am heading to the right department as I continue with the testing/diagnostic. Thank you.

Actions: | Forward |
Answer


Name 

Email 

Security code
Enter the text as shown above


E-Mail me when someone replies to this post
Answer by Dr Dennis S, MD  on Wed 28, Jul 2010 08:07pm:

Hi Miya. Do you also have the differential count of your cbc? Your white blood cell count is lower than normal, which could mean that there is an ongoing infection. An empiric antibiotic therapy can be instituted after appropriate cultures are done. Other causes of decrease in white blood cell count include intake of certain drugs like penicillins and steroids. Autoimmune disorders and hematologic disorders are also causes. Aside from consulting a rheumatologist, you may also want to consult a hematologist and/or an infectious disease specialist for further evaluation. Regards.

If you find the site useful, please consider making a donation.  Click the button to donate.   

Please rate my answer (select the stars, no need to log in.)  


Follow up:

Clarification by miya on Thu 29, Jul 2010 06:42pm:
Yes, it appears to be a CBC w/differential.  Would you like some of those numbers? I am taking no other drugs
(incidentally, am allergic to penicillins).   Doctor said he wanted to do the PE/IFE to identify the reason
for the elevated protein and check for indication of Multiple Myeloma.  The results state there was no M-spike
observed. However, Immunoglobulin M came back high, as I said.  Immunofixation result showed an apparent
Polyclonal Gammopathy; IGM - Kappa lambda typing appear increased. No fever or unusual symptoms since last
batch of tests run a couple of months ago, however, the blood counts have changed from the normal results from
a couple months ago.  I am experiencing pain and feeling of fullness that has been waking me up at night since
this batch of tests done last week. Perhaps spleen?  He also ordered an MRI for an apparent complex partial
seizure he believes I had in his office (thought it was blood sugar, but came back normal when he tested it
there) which I haven't had performed as of yet. -- Hepatitis B/C antigens, Thyroid Peroxidase,
Thyroglobulin antibodies, Lyme, and ANA all came back negative.  Rheumatoid factor, C-reactive tests done
prior to this (recently) were negative.  Complete metabolic panel, T-Cell activation, CD-8 subsets, T + B
Lymphocyte diff., Helper T- Lymph CD-4 and Kappa Lambda free light chains were also tested.  Any further
insights with this information?  I assume they cross-evaluate their findings with other specialists outside
the rheumatology dept., but will request a hematologist and/or infectious disease specialist, if I find that
they do not.  Thank you.
Clarification by miya on Thu 29, Jul 2010 06:47pm:
Sorry, I didn't specify where the pain was:  just below my left ribs, left/mid side of abdomen, hence
'spleen'.  Thanks.

This question is open for comments.  Please share your opinion.

Comments


Name 

Email 

Security code
Enter the text as shown above


E-Mail me when someone replies to this post
Other cancer questions you might be interested in.
  1. Cancer? fever and a pain on the left side of my body near my ovaries and a pain near my liver  (Answered) - Viewed 7532 times   Back in august I had an MRI, because of severe headaches, nausea, loss of feeling in myy right hand, and fainting( dizzines too)...
  2. sclc metastasized to lymph nodes and bones-stage IV  (Answered) - Viewed 1858 times   Which counts in your CBC blood work tell if the chemo is working? Her hemoglobin has been 9.8 9.2 8.1 8.2after a transfusion it ...
  3. Cancer uteri after successful radiotherapy of cervical cancer  (Answered) - Viewed 2345 times   Woman, 65 yo, with hystory of myoma uteri, diabetes and hypertension has been diagnosed with cervical cancer stage IIb-III(verif...
  4. Multinodal cabcer uteri - effective treatment of lymphostasis/edema  (Answered) - Viewed 2499 times   Woman, 65 yo, with history of myoma uteri, diabetes and hypertension has been diagnosed with cervical cancer stage IIb-III(verif...
  5. hemoglobin D disease  (Answered) - Viewed 2369 times   i am a pediatric oncologist in iraq, i have a case of hemoglobin D diseas, i just want to know any thing about this disease. th...
  6. Differential WBC counts..does it mean anything?  (Answered) - Viewed 3376 times   I Had a routine blood test done during physical exam in 2008 and there was a difference observed in WBC differential counts. (Lo...
  7. female, 48, chronic cough, servere anemia  (Answered) - Viewed 1933 times   hello there, i have a question regarding my mum. she is 48, on no medications, never had any health problems in her life. for...
  8. Melanoma metastasis  (Answered) - Viewed 1432 times   Dear doctor, My father (age 58, non-smoker, previous health condition excellent) was diagnosed with metastatic malignant mela...
  9. Soft-tissue tumor in foot  (Answered) - Viewed 2358 times   I have a soft tissue tumor in my left foot, between the first and second metatarsal. It is inside of my foot, just deep to the ...
  10. lymphoma  (Answered) - Viewed 1579 times   Bone marrow biopsy shows: (...a white count of 7.2 hemoglobin 12.2 MCV 86 platelet count 185 and approximate differential of 50...

 
What users are searching right now on Ask an oncologist now:
Colorectal252520Cancer     nodule chin     high20anc     Search for answers     Search for answers     ihaveabump     Search for answers     Search for answers     pth20peptide     Search for answers     Search for answers     Search for answers     Search for answers     Search for answers     Search for answers     lymphoma20of20the20jaw     moels     vaginaandrectumlump     aboutplaisirsexuelaftercancer     anal cancer survivor symptoms     Search for answers     Search for answers     Search for answers     Search for answers     would20high20creatine20kinase20and20immunoglobuline20e20leavels20be20atrributed20to20having20b20cell20lymphoma     Search for answers     Search for answers     Search for answers     bladdercancerstage3nodepositive     Search for answers     Search for answers     Search for answers     Search for answers     cll20leukemia     Search for answers     Search for answers     ihaveasmallblackbluelumpontheinsideofmymouth     Search for answers     Search for answers     colon20cancer20stage203     Search for answers     Search for answers     gum     ResultZessTinisag     lymphocytes count low lumps armpits     WHAT20SYMPTONS20CAN20YOU20HAVE20IF20THE20PETUNIA20GLAND20IS20NOT20NORMAL     recovery20after20abnormal20cells     tiny restriction in the gamma region     painfulandswollenlymph4918252520Enter252520your252520comments252520here252520nodular     with20end20stage20liver20cancer20can20your20liver20burst     what20does20IgM20kappa20monoclonal20protein20detected20in20urine20immunofixation20mean     abnormal wbc     bone     nodules20on20lungs20and20liver     lumpinthighmucsle     brain20tumor20in20cerebellum20region20with20no20sympthons     high Iga     ceafactr     BladderCancer     why20cant20children20get20lung20cancer20when20they20smoke     Lung20Cancer     breat20biopsy20with20high20grade20of20necrosis20and20abdnormal20cells     Search for answers     Search for answers     enlargedlymphnodesonbackofheadandneck     Search for answers     Search for answers     canyouhavepainfromcancerwithoutatumor     IG     Right side pain with blood in my sperm     2cm     Search for anIgG kappa paraproteinemiaswers     Search for answers     igga20kappa20monoclonal20protein     how20to20read20a20colon20ct20scan     brain     Serum20Immunofixation20test20result2020What20does20IgG20Kappa20monoclonal20protein20detected20in20serum20immunofixation20test20mean     girl     heratomas20en20espaol     Search for answers     Search for answers     survivalrate     invasive20ductal20adenocarcinoma     bacteria     I have a rash started on my feet     Search for answers     Search for answers     i20have20been20diagnosed20with20atypical20ductal20hyperplasia20will20my20sons20need20to20be20concerned     Search for answers     Search for answers     lymphoma     Search for answers     Search for answers     Search for answers     Search for answers     survival     no cough lung cancer     liposarcoma     daily20periods     data     

©2011 - Ask an oncologist now  |  All Rights Reserved
The site is not a replacement for professional medical opinion, examination, diagnosis or treatment. Always seek the advice of your medical doctor or other qualified health professional before starting any new treatment or making any changes to existing treatment. Do not delay seeking or disregard medical advice based on information written by any author on this site. No health questions and information on askanoncologistnow is regulated or evaluated by the Food and Drug Administration and therefore the information should not be used to diagnose, treat, cure or prevent any disease without the supervision of a medical doctor. Posts made to these forums express the views and opinions of the author, and not the administrators, moderators, or editorial staff and hence askanoncologistnow and its principals will accept no liabilities or responsibilities for the statements made.

Home | Terms & Conditions | Contact Us | Frequently Asked Questions | Disclaimer | Privacy Policy | Advertise with us
Stats