Home   Recent Questions   Testimonials   FAQs


This question was answered on Wed 28, Jul 2010 08:07pm by Dr Dennis S, MD

High IGM, RBC, Hemoglobin, Hematocrit and low WBC


    
Asked by miya (Female; 38; extreme fatigue, bone pain in leg, ribs, back shoulder blade and joints, weight loss, poor appetite, hair loss, weakness, mental confusion, impaired memory, seizure history, impaired immune response, Mono at 15 and relapsing/chronic EBV ) on Tue 27, Jul 2010 04:19pm
Priced at $29.00

A recent blood test showed high protein levels (8.4), so my doctor ordered a PE and IFE, CBC among other tests to follow-up. The results of those tests showed: WBC: 3.6 (low), RBC: 5.54 (high), Hemoglobin: 17.1 (high), Hematocrit: 49.9 (high), and IGM 242 (high) with 'Kappa and lambda typing appearing increased.' The PE scan is pending. Sed rate is 1. Can you help me to interpret these findings? Prior to this, I had an appointment with The Cleveland Clinic in Ohio set for August 12 with their rheumatology/immunology dept. and am wondering also if I am heading to the right department as I continue with the testing/diagnostic. Thank you.

Actions: | Forward |
Answer


Name 

Email 

Security code
Enter the text as shown above


E-Mail me when someone replies to this post
Answer by Dr Dennis S, MD  on Wed 28, Jul 2010 08:07pm:

Hi Miya. Do you also have the differential count of your cbc? Your white blood cell count is lower than normal, which could mean that there is an ongoing infection. An empiric antibiotic therapy can be instituted after appropriate cultures are done. Other causes of decrease in white blood cell count include intake of certain drugs like penicillins and steroids. Autoimmune disorders and hematologic disorders are also causes. Aside from consulting a rheumatologist, you may also want to consult a hematologist and/or an infectious disease specialist for further evaluation. Regards.

If you find the site useful, please consider making a donation.  Click the button to donate.   

Please rate my answer (select the stars, no need to log in.)  


Follow up:

Clarification by miya on Thu 29, Jul 2010 06:42pm:
Yes, it appears to be a CBC w/differential.  Would you like some of those numbers? I am taking no other drugs
(incidentally, am allergic to penicillins).   Doctor said he wanted to do the PE/IFE to identify the reason
for the elevated protein and check for indication of Multiple Myeloma.  The results state there was no M-spike
observed. However, Immunoglobulin M came back high, as I said.  Immunofixation result showed an apparent
Polyclonal Gammopathy; IGM - Kappa lambda typing appear increased. No fever or unusual symptoms since last
batch of tests run a couple of months ago, however, the blood counts have changed from the normal results from
a couple months ago.  I am experiencing pain and feeling of fullness that has been waking me up at night since
this batch of tests done last week. Perhaps spleen?  He also ordered an MRI for an apparent complex partial
seizure he believes I had in his office (thought it was blood sugar, but came back normal when he tested it
there) which I haven't had performed as of yet. -- Hepatitis B/C antigens, Thyroid Peroxidase,
Thyroglobulin antibodies, Lyme, and ANA all came back negative.  Rheumatoid factor, C-reactive tests done
prior to this (recently) were negative.  Complete metabolic panel, T-Cell activation, CD-8 subsets, T + B
Lymphocyte diff., Helper T- Lymph CD-4 and Kappa Lambda free light chains were also tested.  Any further
insights with this information?  I assume they cross-evaluate their findings with other specialists outside
the rheumatology dept., but will request a hematologist and/or infectious disease specialist, if I find that
they do not.  Thank you.
Clarification by miya on Thu 29, Jul 2010 06:47pm:
Sorry, I didn't specify where the pain was:  just below my left ribs, left/mid side of abdomen, hence
'spleen'.  Thanks.

This question is open for comments.  Please share your opinion.

Comments


Name 

Email 

Security code
Enter the text as shown above


E-Mail me when someone replies to this post
Other cancer questions you might be interested in.
  1. Cancer? fever and a pain on the left side of my body near my ovaries and a pain near my liver  (Answered) - Viewed 7793 times   Back in august I had an MRI, because of severe headaches, nausea, loss of feeling in myy right hand, and fainting( dizzines too)...
  2. sclc metastasized to lymph nodes and bones-stage IV  (Answered) - Viewed 2010 times   Which counts in your CBC blood work tell if the chemo is working? Her hemoglobin has been 9.8 9.2 8.1 8.2after a transfusion it ...
  3. Cancer uteri after successful radiotherapy of cervical cancer  (Answered) - Viewed 2482 times   Woman, 65 yo, with hystory of myoma uteri, diabetes and hypertension has been diagnosed with cervical cancer stage IIb-III(verif...
  4. Multinodal cabcer uteri - effective treatment of lymphostasis/edema  (Answered) - Viewed 2657 times   Woman, 65 yo, with history of myoma uteri, diabetes and hypertension has been diagnosed with cervical cancer stage IIb-III(verif...
  5. hemoglobin D disease  (Answered) - Viewed 2529 times   i am a pediatric oncologist in iraq, i have a case of hemoglobin D diseas, i just want to know any thing about this disease. th...
  6. Differential WBC counts..does it mean anything?  (Answered) - Viewed 3498 times   I Had a routine blood test done during physical exam in 2008 and there was a difference observed in WBC differential counts. (Lo...
  7. female, 48, chronic cough, servere anemia  (Answered) - Viewed 2079 times   hello there, i have a question regarding my mum. she is 48, on no medications, never had any health problems in her life. for...
  8. Melanoma metastasis  (Answered) - Viewed 1553 times   Dear doctor, My father (age 58, non-smoker, previous health condition excellent) was diagnosed with metastatic malignant mela...
  9. Soft-tissue tumor in foot  (Answered) - Viewed 2513 times   I have a soft tissue tumor in my left foot, between the first and second metatarsal. It is inside of my foot, just deep to the ...
  10. lymphoma  (Answered) - Viewed 1748 times   Bone marrow biopsy shows: (...a white count of 7.2 hemoglobin 12.2 MCV 86 platelet count 185 and approximate differential of 50...

 
What users are searching right now on Ask an oncologist now:
how20many20paople20a20year20die20from20lung20cancer     whatkindofdietshouldyoubeonforlivercysts     search     un20block20stool     heart feels like it is being squeezed     what is nodule in breast mean     Is it possible to have IFE fir MM when SPEP and UPEP were both     monoclonalproteinwithkappalightchain     upperthigh     whatissidestreamsmoke     tumor markers breast cancer recurrance     lung cancer throwing up blood and black stools     igm20kaopa     wheredoyoutrainorstudy     Cryotherapy     askpancreaticcancerquestions     travel20restrictions20high20elevation     how20to20read20a20colon20ct20scan     have20occasional20wheeze20with20slight20tightness20in20the20throat     phpadmin     what20do20bright20spots20mean20on20colon20ct20scan     bartholinscarcinoma     mesothelioma law firms     bronchial252520cancer     Paraneoplastic syndrom     they found a blood vessel about 1 centimeter in my left lung I have CT scan procedure tomorrow can what could it be     cancer within the vagina is called     lifeaftersurgerywithoutchemobutusingnaturalproductsanddiet68life     thyroid20carcinoma     my sister was treated for cervical cancer and given the oknow 1 year after she has 2 spots on her lungs How is this possible     igg normal     multiple myeloma igg kappa     Iwanttoknowwhatabladdertumorlooks     whatisthenormalreadingforAlfa2globulin     m     pleasehelpwithme675please     asklungcancerquestions     invasive20mamory20carsonoma20with20ductal20and20focal20features     i have a blister like thing below my gumline behind my bottom teeth what could this be     hypogammaglobin     lungnodulesincreaseinsize     ENDOMETRIAL     breast20cancer201420x201420cm     igg20lamda     cervicaladenocarcinoma     What causes a dermoid cyst Frontal lobe     Kraslungcancertreatment     large20liver20cysts     supraclavicular20lymph20nodes     brainand     how20big20are20hemoroids     hpvandanalcancer4921Enteryourcommentsherestarting     Search for answers     Search for answers     Search for answers     Dermoid     ct20scan20safe     recovery252520after252520abnormal252520cells     IG20Panel20Serum     what20is20a20monoclonal20protein     can you live with only one lung     definition of igg monoclonal protein with lambda light chain     what20does20dimpling20in20the20brest20look20like     native     Youngchildwithheadachesandtiredness     Affiliated     definitionofbreastcancer     endocarnitis     Colen20cancer     gastric     BrainCancernumbness     big20spleen20after20chemo20for20dlbc20nhl     itchy20jawline     there20is20a20ump20smaller20than20a20dime20on20the20inside20of20my20thigh20near20my20knee     secondary     how252520substances252520in252520cigarettes252520causes252520lung252520cancer     lymphomaofthejaw     ResultsofaCBCBloodtestHELP696Results     allergic reaction to peanuts symptoms     Annette Charles     do i need chemo after surgery with cea 7     control coughing     Whataretheremissionnumbersforinvasiveductalcarcinoma     gammaglutamyltransferase     what20does20igm20mean     Are20kidney20cysts20cancerous     myeloma20arm20pain     What is meant in a report that states atypical duct hyperplasia of the right breast     back pain carpal tunnel     breast cancer ILC grade 1     WelcometoWigsLaceOfferingwigshairextensionsfalls     What20is20lobular20carcinoma     multifocalinvasive     hemangioma on liver     Waldenstrm     germanmessles     swollen20lymph20nodes20both20armpits     CRP levels     Mga     vtamin b17 are approved for treatement of cancer OR not     

©2011 - Ask an oncologist now  |  All Rights Reserved
The site is not a replacement for professional medical opinion, examination, diagnosis or treatment. Always seek the advice of your medical doctor or other qualified health professional before starting any new treatment or making any changes to existing treatment. Do not delay seeking or disregard medical advice based on information written by any author on this site. No health questions and information on askanoncologistnow is regulated or evaluated by the Food and Drug Administration and therefore the information should not be used to diagnose, treat, cure or prevent any disease without the supervision of a medical doctor. Posts made to these forums express the views and opinions of the author, and not the administrators, moderators, or editorial staff and hence askanoncologistnow and its principals will accept no liabilities or responsibilities for the statements made.

Home | Terms & Conditions | Contact Us | Frequently Asked Questions | Disclaimer | Privacy Policy | Advertise with us
Stats