Home   Recent Questions   Testimonials   FAQs

This question was answered on Wed 28, Jul 2010 07:07pm by Dr Dennis S, MD

High IGM, RBC, Hemoglobin, Hematocrit and low WBC

Asked by miya (Female; 38; extreme fatigue, bone pain in leg, ribs, back shoulder blade and joints, weight loss, poor appetite, hair loss, weakness, mental confusion, impaired memory, seizure history, impaired immune response, Mono at 15 and relapsing/chronic EBV ) on Tue 27, Jul 2010 03:19pm
Priced at $29.00

A recent blood test showed high protein levels (8.4), so my doctor ordered a PE and IFE, CBC among other tests to follow-up. The results of those tests showed: WBC: 3.6 (low), RBC: 5.54 (high), Hemoglobin: 17.1 (high), Hematocrit: 49.9 (high), and IGM 242 (high) with 'Kappa and lambda typing appearing increased.' The PE scan is pending. Sed rate is 1. Can you help me to interpret these findings? Prior to this, I had an appointment with The Cleveland Clinic in Ohio set for August 12 with their rheumatology/immunology dept. and am wondering also if I am heading to the right department as I continue with the testing/diagnostic. Thank you.

Actions: | Forward |



Security code
Enter the text as shown above

E-Mail me when someone replies to this post
Answer by Dr Dennis S, MD  on Wed 28, Jul 2010 07:07pm:

Hi Miya. Do you also have the differential count of your cbc? Your white blood cell count is lower than normal, which could mean that there is an ongoing infection. An empiric antibiotic therapy can be instituted after appropriate cultures are done. Other causes of decrease in white blood cell count include intake of certain drugs like penicillins and steroids. Autoimmune disorders and hematologic disorders are also causes. Aside from consulting a rheumatologist, you may also want to consult a hematologist and/or an infectious disease specialist for further evaluation. Regards.

If you find the site useful, please consider making a donation.  Click the button to donate.   

Please rate my answer (select the stars, no need to log in.)  

Follow up:

Clarification by miya on Thu 29, Jul 2010 05:42pm:
Yes, it appears to be a CBC w/differential.  Would you like some of those numbers? I am taking no other drugs
(incidentally, am allergic to penicillins).   Doctor said he wanted to do the PE/IFE to identify the reason
for the elevated protein and check for indication of Multiple Myeloma.  The results state there was no M-spike
observed. However, Immunoglobulin M came back high, as I said.  Immunofixation result showed an apparent
Polyclonal Gammopathy; IGM - Kappa lambda typing appear increased. No fever or unusual symptoms since last
batch of tests run a couple of months ago, however, the blood counts have changed from the normal results from
a couple months ago.  I am experiencing pain and feeling of fullness that has been waking me up at night since
this batch of tests done last week. Perhaps spleen?  He also ordered an MRI for an apparent complex partial
seizure he believes I had in his office (thought it was blood sugar, but came back normal when he tested it
there) which I haven't had performed as of yet. -- Hepatitis B/C antigens, Thyroid Peroxidase,
Thyroglobulin antibodies, Lyme, and ANA all came back negative.  Rheumatoid factor, C-reactive tests done
prior to this (recently) were negative.  Complete metabolic panel, T-Cell activation, CD-8 subsets, T + B
Lymphocyte diff., Helper T- Lymph CD-4 and Kappa Lambda free light chains were also tested.  Any further
insights with this information?  I assume they cross-evaluate their findings with other specialists outside
the rheumatology dept., but will request a hematologist and/or infectious disease specialist, if I find that
they do not.  Thank you.
Clarification by miya on Thu 29, Jul 2010 05:47pm:
Sorry, I didn't specify where the pain was:  just below my left ribs, left/mid side of abdomen, hence
'spleen'.  Thanks.

This question is open for comments.  Please share your opinion.




Security code
Enter the text as shown above

E-Mail me when someone replies to this post
Other cancer questions you might be interested in.
  1. Cancer? fever and a pain on the left side of my body near my ovaries and a pain near my liver  (Answered) - Viewed 7962 times   Back in august I had an MRI, because of severe headaches, nausea, loss of feeling in myy right hand, and fainting( dizzines too)...
  2. sclc metastasized to lymph nodes and bones-stage IV  (Answered) - Viewed 2088 times   Which counts in your CBC blood work tell if the chemo is working? Her hemoglobin has been 9.8 9.2 8.1 8.2after a transfusion it ...
  3. Cancer uteri after successful radiotherapy of cervical cancer  (Answered) - Viewed 2599 times   Woman, 65 yo, with hystory of myoma uteri, diabetes and hypertension has been diagnosed with cervical cancer stage IIb-III(verif...
  4. Multinodal cabcer uteri - effective treatment of lymphostasis/edema  (Answered) - Viewed 2791 times   Woman, 65 yo, with history of myoma uteri, diabetes and hypertension has been diagnosed with cervical cancer stage IIb-III(verif...
  5. hemoglobin D disease  (Answered) - Viewed 2653 times   i am a pediatric oncologist in iraq, i have a case of hemoglobin D diseas, i just want to know any thing about this disease. th...
  6. Differential WBC counts..does it mean anything?  (Answered) - Viewed 3576 times   I Had a routine blood test done during physical exam in 2008 and there was a difference observed in WBC differential counts. (Lo...
  7. female, 48, chronic cough, servere anemia  (Answered) - Viewed 2176 times   hello there, i have a question regarding my mum. she is 48, on no medications, never had any health problems in her life. for...
  8. Melanoma metastasis  (Answered) - Viewed 1631 times   Dear doctor, My father (age 58, non-smoker, previous health condition excellent) was diagnosed with metastatic malignant mela...
  9. Soft-tissue tumor in foot  (Answered) - Viewed 2596 times   I have a soft tissue tumor in my left foot, between the first and second metatarsal. It is inside of my foot, just deep to the ...
  10. lymphoma  (Answered) - Viewed 1826 times   Bone marrow biopsy shows: (...a white count of 7.2 hemoglobin 12.2 MCV 86 platelet count 185 and approximate differential of 50...

What users are searching right now on Ask an oncologist now:
naso pharyneal mass     Mymotherinlawhasbeendiagonisedwith     corityarty     ovary     Nodules20on20lungs20and20liver     WhatdoyouthinkpleaseCellsafterbiopsywerehighgradewithnecrosis108What     napsin     ovary20pain     POORLYDIFFERENTIATEDCARCINOMASUGGESTIVEOFADENOCARCINOMAPOUCHOFDOUGLAS     Ihavewhatseemstobe     Ductal20derivation     prostrate     thorasiccancer     ovarian20complex20cyst     breastcancerstagingpt1c     native20american20white20wolf     the treatment of skin disease     igmkappa     Can20I20take20tamoxifen20and20hcg     neck20sore20lump20in20back20of20neck     constipation20during20chemotherapy     what20is20the20acceptable20range20of20igg20kappa     how20do20they20take20a20lung20byopsy     recoveryandpiercings     scf concentrated 80x reveal a trace of immunofixation igg kapa monoclonal imunoglobulin migrating in the gamma region     colorectalcancer     premestrual breast cancer ovariectomy     cervical20cancer20and20calcium20level     morfina20e20esfincter20de20oddi     what20are20signs20of20prostate20cancer     breastcancer4849 Enter your comments here scheme     porno indir     stop20chemo     heart20hurting     polyclonal20iggigaigm20immunoglobulins20and202identifies20an20IgM20kappa20monoclonal20immunoglobulin     search20for20answers     rheumatoid factor 12     bumponanus     Young20child20with20headaches20and20tiredness     blast20s20in20brain20cancer     Search for answers     Search for answers     google     behind20ear     drroytolentino     e cadherin     shadowonlung     Search for answers     Search for answers     CouldIhaveacancergoingonRecentbloodworkinterpretationshowedatinyrestrictioninthegammaregionpossiblyindicatingthepresenceofalymphoproliferativeprocessItisbeingrecommendedtohaveimmunofixationofurineorquantifica     what causes cancer in neonates     follicular mucinosis     stomach cancer     myeloma20prognosis     role of pancreas     please     igg20kappa20monoclonal20immunoglobulin     polyclonalgammopathyiga     primary20myelofibrosis     igG normal monoclponal peak     bartholins     Multiple     PossiblelungcancerwithmetstocerebellumMRIofthebrainandCToflungs199Possiblelung     does20lung20cancer20return20after20820years     VITAMIND     anaplasticoligoastrocytomag     lost 20 lbs in 2 months fatigue palpatations     SerumImmunofixationtest     spot20ct20scan     IgGkappamonoclonalbandpresentwithoutspikes     secondarycnslymphomas     headache20in20children     flcratio     ifIhavefreekappalightchaininthehighnormalrangedoIhavemyeloma     faint20ill20defined20band20of20igm20lambda20in20serum     igmkappamonoclonalbandpresentwhatdoesthismean     WhatisIgMKappaMonoclonalProtein     enlarged peripancreatic lymph nodes     Search for answers     Search for answers     subcutaneoustumor     Search for answers     ihaveasmallblackbluelumpontheinsideofmymouth     ItchingCouldthisbe     is20a20female20oncologist20able20to20start20a20family20and20become20a20proper20present20mother     what20is20a20igg20lambda20monoclonal20band     iga 413     Lynch syndrome     emetreatohnomiscancer     ItchingCouldthisbe     How20big20is20big     would20high20creatine20kinase20and20immunoglobuline20E20leavels20be20atrributed20to20having20B20cell20lymphoma     Lump20in20the20bottom20of20mouth     breast cancer grade 3 chemo or not     Search20for20answersIGM20LAMBDA20MONOCLONAL20IMMUNOGLOBULIN     using20a20sitz20bath20to20onplug20stool     high20wbc20and20lymphocytes     annette     abn20protein20band     thyroid20cancer20and20rotator20cuff20tears     

©2011 - Ask an oncologist now  |  All Rights Reserved
The site is not a replacement for professional medical opinion, examination, diagnosis or treatment. Always seek the advice of your medical doctor or other qualified health professional before starting any new treatment or making any changes to existing treatment. Do not delay seeking or disregard medical advice based on information written by any author on this site. No health questions and information on askanoncologistnow is regulated or evaluated by the Food and Drug Administration and therefore the information should not be used to diagnose, treat, cure or prevent any disease without the supervision of a medical doctor. Posts made to these forums express the views and opinions of the author, and not the administrators, moderators, or editorial staff and hence askanoncologistnow and its principals will accept no liabilities or responsibilities for the statements made.

Home | Terms & Conditions | Contact Us | Frequently Asked Questions | Disclaimer | Privacy Policy | Advertise with us