Hi there.
From what you have described I can tell that your sister underwent "neoadjuvant" chemotherapy and radiation therapy. This means that the radiation and chemo was given "before" the definitive operation is done. Neoadjuvant treatment is usually given for large primary tumors, those that may already invade other organs, or those with multiple lymph node spread.
The definitive procedure is still to do the surgical resection. After the surgery, it is recommended that she undergo "adjuvant" chemotherapy. Adjuvant chemotherapy aims to decrease the chance of the tumor recurring or spreading and it will usually take 6 more months of chemotherapy to achieve this end.
There are several drugs that can be given for the adjuvant treatment of colorectal cancers including 5-FU, Leucovorin, Oxaliplatin, and Capecitabine used in different combinations and schedules.
Surveillance after the surgery and chemotherapy is also important so that the early signs of recurrence can be detected. Surveillance can be in the form of imaging studies like CT scan, and/or blood tests for tumor markers.
I suggest you discuss all of these things with your oncologist, and I'm hoping for an uneventful surgery and quick recovery.
Regards..
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