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This question was answered on Thu 25, Sep 2008 12:37pm by Dr Heinrik M, MD

h. pylori possible colorectal cancer


    
Asked by grp (Female; 48; high cholesterol take lipitor and zetia ) on Thu 25, Sep 2008 11:26am
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I have just been diagnosed with h. pylori infection. I am on 14 days of triple antibiotics-prevacid, biaxin, and amoxycillin. I had suffered from constipation off and on for almost three years, so I had a colonoscopy done in July. Everything was normal.Even my Ct scans with barium drink and IV contrast dye. My question is, now I have several bowel movements a day. They are not diarrhea or bloody-my stool guaiacs were normal and also FOBT. They are formed movements. How can I go from constipation to this? Could it be the meds? I never feel completely empty. I never throw up or have nausea. Will these meds cure me, and do I necessarily have an ulcer now? Thank you

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Answer by Dr Heinrik M, MD  on Thu 25, Sep 2008 12:37pm:

Hi, I understand the surprise when symptoms shift from one spectrum to another. H pylori is not associated with colorectal cancer. There are cancers associated with it, they would be stomach cancers. If you had an endoscopy procedure done and I am suspecting you had, these tumors would be visible. The elimination of H pylori at the current time would of course lower your risk for subsequent development of cancer. The best way to see if you do have an ulcer is to check your endoscopy report. If you had a breath test instead of an endoscopy.Aside from ulcers, inflammation/swelling of the stomach lining is caused by H pylori, so you do not necessarily have an ulcer present. The current bowel movements may be due to a couple of factors. The first is that antibiotics can disrupt the normal growth of friendly microorganisms, and hence some may be favored to over grow more than others – the consequences would be diarrhea (this is actually defined as a change in frequency or character of stool). The second is that the reduction in stomach acid (which is again part of the therapy) may give you a bloated feeling. A bloated stomach would trigger signals that new food has entered, and a need to defecate would be initiated. The colonoscopy is the best test to screen for colon cancer. There is a robust pattern of disease starting as benign growths gradually progressing to malignancy over a course of ten years. Thus it is unlikely to get colon cancer all of the sudden. Stay positive.

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Follow up:

Clarification by grp on Thu 25, Sep 2008 11:48am:
Also, I am wondering if frequent bowel movements is something serious.

Comments:

Comment by Dr Heinrik M, MD on Fri 26, Sep 2008 10:08am: Hi, There is a wide variation as to how frequent bowel movements are. Some people may need to defecate more than once in a day, there are even people who may need to do so after each meal. The increased frequency would be worrisome if there is a reason to suspect malabsorption (in which the increased frequency is due to the decreased amount of material absorbed by the guts). This would be suspected if the stool is loose, or there seems to be an oily film floating in the water, or if there seems to be ongoing weight loss. You have described your stool as formed, so at present, this increased frequency may be at most a disruption in your accustomed daily schedule more than anything else. The guts also have their own independent nervous system. Hence, it may take a few days before things return to normal, even though your routine diet and activities have resumed. Stay positive.

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