possible medical conditions with the symptoms described below

Hi, Your concerns about losing weight are valid, and cancer is indeed one condition to think about. Weight loss would generally raise suspicion of a gastrointestinal tract cancer. For the upper tract which is from the mouth down the throat- the symptoms would be fairly prominent. Patients generally know they are losing weight because of pain associated with swallowing. Hence, an examination would be directed to the mouth and the throat. This seems to be absent in your case. The middle part of the tract would be a bit challenging. There may be some aches and pains associated with cancers of the stomach (but this is upper, nearer the ribs than the pelvis, or above the belly button). There may also be occasional constipation or diarrhea, bleeding in the stool, for the large intestines. Cancer of the large intestines are much more common, and if it the pain is more to the lower left, then this may mean the descending part of the large intestine. Pain isn’t a very common symptom though in the absence of obstruction (hence patients would observe/report the constipation or the changes in stool caliber more than the pain). While a barium enema is a good test, it may not be able to capture a small cancer unlike a colonoscopy. There is a valid argument however, that usually small cancers to be missed by the barium enema would not likely cause any significant weight loss. However, a colonoscopy would give the opportunity for a biopsy, and the discomfort may not be much different from the enema. Cancers aside from the digestive tract could also produce weight loss, but these are usually in advanced stages, in which a clear diagnosis of cancer would easily be found. The bruising could be a symptom of a cancer affecting blood or liver. Alternatively, it may simply be a consequence of inadequate nutrition. The same may be said of the headaches and the nausea, as well as the thinning of the hair. Some other things to think about would be to investigate the thyroid gland. Over-activity may present itself with weight loss. The pain may also be associated with the pancreas, and abnormal digestion malabsorption and hence weight loss may follow. If you have a significant alcohol history then this may be something to investigate further. Malabsorption syndromes from diet are sometimes overlooked as well. Perhaps a diet diary would be in order. Recently, some cases of weight loss due to chewing/bubble gum has been characterized. It seems that the current diagnostic plan is reasonable. Stick with it, there are cases in which it may take some time before the disease shows enough signs for it to be recognizable. Stay positive.

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